Festem is a statistical method for the direct selection of cell-type markers for downstream clustering. Festem distinguishes marker genes with heterogeneous distribution across cells that are cluster informative.
For analysis codes for paper "Directly selecting differentially expressed genes for single-cell clustering analyses", see https://github.com/XiDsLab/Festem_paper.
To install Festem, start R and enter:
if (!require("pak", quietly = TRUE))
install.packages("pak")
pak::pkg_install("XiDsLab/Festem")
For detailed usage of Festem, please refer to our protocol at XXX.
- Chen, Z., Wang, C., Huang, S., Shi, Y., & Xi, R. (2024). Directly selecting cell-type marker genes for single-cell clustering analyses. Cell Reports Methods, 4(7). https://doi.org/10.1016/j.crmeth.2024.100810
- Wang, C., Chen, Z., & Xi, R. (2023). Feature screening for clustering analysis. arXiv preprint arXiv:2306.12671. https://arxiv.org/abs/2306.12671